Movie 5.
ER packing in Rab1 depleted embryos results in shortened spindle. Time lapse imaging of the ER (UAS-RFP:ER) and spindle microtubules (Jupiter:GFP) in Rab1 embryos during cell cycle 11 showing failed division and subsequent nuclear fallout. Images were collected at 5s intervals and are displayed at 10 frames per second. Total developmental time= 9.5 min. Scale bar=5μm.
Dysregulation of the endoplasmic reticulum blocks recruitment of centrosome-associated proteins resulting in mitotic failure
Development 2023. 150:None-None; doi: 10.1242/dev.201917