Movie 6.
ER and mitotic phenotypes are rescued in Dynein inhibited Rab1 embryos. Time lapse imaging of the ER (UAS-GFP:ER) in a Rab1 depleted embryo injected with Dynein inhibitor, CiliobrevinD during cell cycle 11. Images were collected at 5s intervals and are displayed at 15 frames per second. Total developmental time= 9 min 10s. Scale bar=10μm.
Dysregulation of the endoplasmic reticulum blocks recruitment of centrosome-associated proteins resulting in mitotic failure
Development 2023. 150:None-None; doi: 10.1242/dev.201917