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Movie 3.

Live imaging of the dynamic behaviours exhibited by the biliary network expressing tg(tp1:H2B-mCherry) as hepatocytes are dying, shortly after LiverZap activation (N=1; n=2). Frames were acquired every 20 minutes from 5 hpi to 24 hpi.

LiverZap: a chemoptogenetic tool for global and locally restricted hepatocyte ablation to study cellular behaviours in liver regeneration

Elizabeth M. G. Ambrosio, Charlotte S. L. Bailey, Iris A. Unterweger, Jens B. Christensen, Marcel P. Bruchez, Pia R. Lundegaard, and Elke A. Ober

Development 2024. 151:None-None; doi: 10.1242/dev.202217