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Movie 2.

Disrupted secondary sprouting in a tie1 mutant embryo. Time-lapse recording in the trunk of a Tg(kdrl:EGFP);Tg(lyve1:DsRed) tie1-/- embryo from 37 hpf taken every 30 min by confocal microscopy. Elapsed time (h:min:sec). Lateral view, anterior to the left. In the tie1 mutant, sprouting ECs extend their protrusions but do not migrate dorsally.

Angpt1 binding to Tie1 regulates the signaling required for lymphatic vessel development in zebrafish

Nanami Morooka, Ning Gui, Koji Ando, Keisuke Sako, Moe Fukumoto, Urara Hasegawa, Melina Hußmann, Stefan Schulte-Merker, Naoki Mochizuki, and Hiroyuki Nakajima

Development 2024. 151:None-None; doi: 10.1242/dev.202269