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Movie 1.

Light sheet time lapse movie of the supraorbital arch of an intact wild-type mouse embryo that harbors a transgenic fluorescent cell membrane label (Wnt5a+/-; R26-mTmG) at E10.5. The orbit is apparent at the bottom of the field. This coronal view of a mediolateral (leftto-right) and apicobasal (top-bottom) plane shows evidence of tissue remodeling with basal narrowing in coronal section and apical extension.

Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion

Nikaya Polsani, Theodora Yung, Evan Thomas, Melissa Phung-Rojas, Isha Gupta, Julie Denker, Kimberly Lau, Xiaotian Feng, Beatriz Ibarra, Sevan Hopyan, and Radhika P. Atit

Development 2024. 151:None-None; doi: 10.1242/dev.202596