Movie 3.
Time lapse light sheet movie of a Wnt1:Cre;mTmG embryo at E10.5. The field of view is within the apical region of supraorbital mesenchyme near the adjacent lateral ectoderm on the left. Cell membranes are sparsely labelled in green due to mosaicism of the Cre allowing for visualization of filopodia. Filopodial extension precedes movement of the cell body (dark) toward the apex.
Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion
Development 2024. 151:None-None; doi: 10.1242/dev.202596