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Movie 4.

HSPC lysosomes polarization upon interaction with osteoblast. Time-lapse monitoring with transmitted light and fluorescence of live HSPCs in contact with osteoblast. HSPC is labelled with LysoBrite (blue) for lysosome live staining. Time is indicated in hours: minutes. Scale bar: 20 μm.

Heterotypic interaction promotes asymmetric division of human hematopoietic progenitors

Adrian Candelas, Benoit Vianay, Matthieu Gelin, Lionel Faivre, Jerome Larghero, Laurent Blanchoin, Manuel Théry, and Stéphane Brunet

Development 2024. 151:None-None; doi: 10.1242/dev.203088

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