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Movie 5.

3D reconstruction of a HSPC dividing perpendicularly to osteoblast cell surface. Actin appears in white, chromosomes in blue, and the centrosome in magenta. Osteoblast was seeded in a 50μm diameter microwell.

Heterotypic interaction promotes asymmetric division of human hematopoietic progenitors

Adrian Candelas, Benoit Vianay, Matthieu Gelin, Lionel Faivre, Jerome Larghero, Laurent Blanchoin, Manuel Théry, and Stéphane Brunet

Development 2024. 151:None-None; doi: 10.1242/dev.203088