Movie 5

Longitudinal axis view of a the heart from a Tg(cmlc2:CreER;bactin2:loxP-mCherry-STOP-loxP-DTA176)^pd36 zebrafish seven days after treatment with 4-HT to induce DTA myocarditis. There is severely depressed ventricular contractile function. Zebrafish were able to survive despite severe cardiomyopathy, instead relying on atrial contraction to drive cardiac output.