To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 4 Time-lapse images showing brain vessel development in homozygous fn40a mutant Tg(fli1a:nuc-eGFP) embryo from 36 to 48 hpf at 20-min intervals. Note vessel rupture and hematoma formation. Miconazole protects blood vessels from MMP9-dependent rupture and hemorrhage Ran Yang, Yunpei Zhang, Dandan Huang, Xiao Luo, Liangren Zhang, Xiaojun Zhu, Xiaolin Zhang, Zhenming Liu, Jing-Yan Han, and Jing-Wei Xiong Disease Models and Mechanisms 2017. 10:337-348; doi: 10.1242/dmm.027268 Download Original Video