3D reconstruction of the 124I DPA-713 PET/CT imaging of a M. tuberculosis-infected rabbit. M. tuberculosis-infected rabbit at 24 hours post-tracer injection seen in Fig. 5. As with the uninfected animal, the PET signal is seen at the site of injection (ear vein) as well as the heart. However, unlike the uninfected animal, there is PET signal localization to the brain's right hemisphere, which is the site of the tuberculoma seen on gross pathology in Fig. 5.
Elizabeth W. Tucker, Supriya Pokkali, Zhi Zhang, Vincent P. DeMarco, Mariah Klunk, Elizabeth S. Smith, Alvaro A. Ordonez, Marie-France Penet, Zaver Bhujwalla, Sanjay K. Jain, and Sujatha Kannan
Disease Models and Mechanisms
2016. 9:1497-1506; doi: 10.1242/dmm.027326