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Locomotor behavior of SLICK-H::Ranbp2flox/flox (-/-) mice at day 9 post-tamoxifen administration.

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes

Kyoung-in Cho, Dosuk Yoon, Sunny Qiu, Zachary Danziger, Warren M. Grill, William C. Wetsel, and Paulo A. Ferreira

Disease Models and Mechanisms 2017. 10:559-579; doi: 10.1242/dmm.027730