Supplemental Movie 3
Optical projection tomography of an E17.5 Pdgfrafl/-;Tie2Cre heart and great vessels. The aorta emanates from the right ventricle, while the pulmonary artery emanates from the left ventricle. PA: Pulmonary artery, RV: Right ventricle, LV: Left ventricle.
Pdgfrα functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries
Disease Models and Mechanisms 2017. 10:1101-1108; doi: 10.1242/dmm.029710