Supplemental Movie 3

Optical projection tomography of an E17.5 Pdgfrafl/-;Tie2Cre heart and great vessels. The aorta emanates from the right ventricle, while the pulmonary artery emanates from the left ventricle. PA: Pulmonary artery, RV: Right ventricle, LV: Left ventricle.

Pdgfrα functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries

Haig Aghajanian, Young Kuk Cho, Nicholas W. Rizer, Qiaohong Wang, Li Li, Karl Degenhardt, and Rajan Jain

Disease Models and Mechanisms 2017. 10:1101-1108; doi: 10.1242/dmm.029710