Movie S7
Neutrophil specific knock out components of complex I or III of mitochondrial ETC inhibited neutrophil motility. One-cell stage embryos were injected with constructs that specifically knock out rac2, ndufs2, or uqcrc1 in neutrophils. Neutrophils in the head mesenchyme were imaged using a confocal microscopy at 3 dpf. Scale bar: 50 μm.
Neutrophil-specific knockout demonstrates a role for mitochondria in regulating neutrophil motility in zebrafish
Disease Models and Mechanisms 2018. 11:None-None; doi: 10.1242/dmm.033027