To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Supplementary movie 1 M85CY decorates and bundles peripheral microtubules. HeLa cells were transfected with M85CY-GFP and imaged lived 4 h after transfection. Time is indicated in h:min. Functional differences of short and long isoforms of spastin harboring missense mutation Clément Plaud, Vandana Joshi, Natallie Kajevu, Christian Poüs, Patrick A. Curmi, and Andrea Burgo Disease Models and Mechanisms 2018. 11:None-None; doi: 10.1242/dmm.033704 Download Original Video