Movie S2

Intracerebellar infusion of Cadmium results in motor symptoms in wild type mice. A WT mouse implanted with a cannula in the cerebellum and connected to an osmotic pump filled with 200 mM CdCl2 shown 1 hour, 4 hours and 21 hours post-surgery.

Aberrant cerebellar Purkinje cell activity as the cause of motor attacks in a mouse model of episodic ataxia type 2

Esra Tara, Ariel Vitenzon, Ellen Hess, and Kamran Khodakhah

Disease Models and Mechanisms 2018. 11:None-None; doi: 10.1242/dmm.034181