Movie S5
Long-term dynamics of mouse cells in the fish caudal hematopoietic tissue (3.4 MB). Mouse bone marrow cells were isolated, lineage depleted, labeled with CellTrace Violet and transplanted into nacre-/-, flk1:dsred embryos. The video was made by compiling images taken every 5 minutes for 1 hour and 25 minutes. Pseudo-colored confocal imaging shows mouse cell (green) dynamic displacements and interactions within the fish CHT (red) in a 2 dpf embryo. The lower panel shows only the mouse cells labeled. The timing of the video is shown in the upper right corner.
Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies
Disease Models and Mechanisms 2018. 11:None-None; doi: 10.1242/dmm.034876