Movie S6

Mouse bone marrow derived cells display dynamic behaviors within the fish caudal hematopoietic tissue (19.7 MB). Mouse bone marrow cells were isolated, lineage depleted, labeled with CellTrace Violet and transplanted into nacre-/-, flk1:dsred embryos. The video was made by compiling images taken approx. every 2,6 seconds for 2,8 minutes. Pseudo-colored confocal high magnification imaging throughout the fish CHT of a xenotransplanted 3 dpf embryo shows mouse cells dynamic behavior. Time is indicated in seconds in the upper right corner of the video.

Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies

Margarita Parada-Kusz, Cristina Penaranda, Elliott J. Hagedorn, Anne Clatworthy, Anil V. Nair, Jonathan E. Henninger, Christoph Ernst, Brian Li, Raquel Riquelme, Humberto Jijon, Eduardo J. Villablanca, Leonard I. Zon, Deborah Hung, and Miguel L. Allende

Disease Models and Mechanisms 2018. 11:None-None; doi: 10.1242/dmm.034876