Movie 2

Visualization of ryr1b-/- mutants lacking C-bend behavior.
Behavioral activities were recorded at 500 frames/sec. Immediately following tactile stimulation to the head, ryr1b mutants reacted with short bursts of weak contractions that result in the larva wiggling in place. These mutants display no C-bend behavior and are unable to swim away from the source of stimulation.

Interactions among ryanodine receptor isotypes contribute to muscle fiber type development and function

Alexis A. Chagovetz, Dana Klatt Shaw, Erin Ritchie, Kazuyuki Hoshijima, and David J. Grunwald

Disease Models and Mechanisms 2020. 13:None-None; doi: 10.1242/dmm.038844