Movie 4

Fly-through visualization of changes in TH staining intensity in average MPTP mouse brain compared to average vehicle mouse control brain. MPTP mouse brain regions with significantly altered average tyrosine hydroxylase signal intensity are delineated in blue (downregulation) or red (upregulation).

Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease

Urmas Roostalu, Casper B. G. Salinas, Ditte D. Thorbek, Jacob L. Skytte, Katrine Fabricius, Pernille Barkholt, Linu M. John, Vanessa Isabell Jurtz, Lotte Bjerre Knudsen, Jacob Jelsing, Niels Vrang, Henrik H. Hansen, and Jacob Hecksher-Sørensen

Disease Models and Mechanisms 2019. 12:None-None; doi: 10.1242/dmm.042200

Download Original Video