Movie 7

Host cell-intrinsic response disrupts Toxoplasma parasitophorous vacuoles in zebrafish macrophages in vivo, related to Figure 7. FIB SEM of two parasites inside a macrophage in the HBV of mpeg1:G/U:mCherry larvae infected with type I Toxoplasma-GFP at 6 hpi. The data was binned to 20 nm3 to fit within the size constraints. Movie shows 860 consecutive slices through the YZ axis, as shown in Fig. 7. Scale bar, 5 μm (top panels) and 1 μm (lower panels). Field of view of 16 x 19 μm in XY.

The zebrafish as a novel model for the in vivo study of Toxoplasma gondii replication and interaction with macrophages

Nagisa Yoshida, Marie-Charlotte Domart, Christopher J. Peddie, Artur Yakimovich, Maria J. Mazon-Moya, Thomas A. Hawkins, Lucy Collinson, Jason Mercer, Eva-Maria Frickel, and Serge Mostowy

Disease Models and Mechanisms 2020. 13:None-None; doi: 10.1242/dmm.043091