Movie 1

Representative timelapse confocal video of red channel images of dynamic, live-cell imaging studies of enteroids derived from p65-DsRedxp/ IκBalpha-eGFP mice, either treated with 100ng/mL TNF alone, or pre-treated with 10μM clarithromycin and subsequently stimulated with TNF.

Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease

Katie Lloyd, Stamatia Papoutsopoulou, Emily Smith, Philip Stegmaier, Francois Bergey, Lorna Morris, Madeleine Kittner, Hazel England, Dave Spiller, Mike H. R. White, Carrie A. Duckworth, Barry J. Campbell, Vladimir Poroikov, Vitor A. P. Martins dos Santos, Alexander Kel, Werner Muller, D. Mark Pritchard, Chris Probert, Michael D. Burkitt, and None None

Disease Models and Mechanisms 2020. 13:None-None; doi: 10.1242/dmm.044040

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