Movie 1

The movie shows a time lapse calcium imaging using Fluo-4. Organoids were treated with 100 μM carbachol, and recorded for 10 minutes. Green fluoresece shows calcium release in the organoid cells. Labial gland derived organoids, day 8.

Inhibition of Alk signaling promotes the induction of human salivary-gland-derived organoids

Shohei Yoshimoto, Junko Yoshizumi, Hiromasa Anzai, Koichiro Morishita, Kazuhiko Okamura, Akimitsu Hiraki, and Shuichi Hashimoto

Disease Models and Mechanisms 2020. 13:None-None; doi: 10.1242/dmm.045054