Epileptiform activity in Kctd7-deficient mice. Representative videos of EEG recording in wild-type control and Kctd7-/- animals. Among these mice, behavioral seizures were noted, consisting of high-frequency runs of spike discharges with a myoclonic head drop, followed in some instances by repetitive grooming movements of the forelimbs.
Justine H. Liang, Jonathan Alevy, Viktor Akhanov, Ryan Seo, Cory A. Massey, Danye Jiang, Joy Zhou, Roy V. Sillitoe, Jeffrey L. Noebels, and Melanie A. Samuel
Disease Models and Mechanisms
2022. 15:None-None; doi: 10.1242/dmm.049642