Movie 1.
Epileptiform activity in Kctd7-deficient mice. Representative videos of EEG recording in wild-type control and Kctd7-/- animals. Among these mice, behavioral seizures were noted, consisting of high-frequency runs of spike discharges with a myoclonic head drop, followed in some instances by repetitive grooming movements of the forelimbs.
Kctd7 deficiency induces myoclonic seizures associated with Purkinje cell death and microvascular defects
Disease Models and Mechanisms 2022. 15:None-None; doi: 10.1242/dmm.049642