Movie 1.

Swimming behaviour in WT. All adults placed into a novel tank swim to the bottom momentarily before resuming standard swimming, balance and buoyancy maintained.

Unexpected phenotypic and molecular changes of combined glucocerebrosidase and acid sphingomyelinase deficiency

Marcus Keatinge, Matthew E. Gegg, Lisa Watson, Heather Mortiboys, Nan Li, Mark Dunning, Deepak Ailani, Hai Bui, Astrid van Rens, Dirk J. Lefeber, Anthony H. V. Schapira, Ryan B. MacDonald, and Oliver Bandmann

Disease Models and Mechanisms 2023. 16:None-None; doi: 10.1242/dmm.049954