Simulated tissue (normal tissue coupling) voltage map showing AP wave propagation elicited by the last pacing stimulus (t=10,000 ms) and the membrane voltage activity thereafter. Simulated conditions are: top left - baseline; bottom left - baseline + ISO; top right - PLN knockdown; bottom right - PLN knockdown + ISO.
Anaïs Kervadec, James Kezos, Haibo Ni, Michael Yu, James Marchant, Sean Spiering, Suraj Kannan, Chulan Kwon, Peter Andersen, Rolf Bodmer, Eleonora Grandi, Karen Ocorr, and Alexandre R. Colas
Disease Models and Mechanisms
2023. 16:None-None; doi: 10.1242/dmm.049962