Movie 2.
Simulated tissue (reduced tissue coupling D×25%) voltage map showing AP wave propagation elicited by the last pacing stimulus (t=10,000 ms) and the membrane voltage activity thereafter. Simulated conditions are: top left - baseline; bottom left - baseline + ISO; top right - tPLN knockdown; bottom right - PLN knockdown + ISO.
Multiplatform modeling of atrial fibrillation identifies phospholamban as a central regulator of cardiac rhythm
Disease Models and Mechanisms 2023. 16:None-None; doi: 10.1242/dmm.049962