Movie 4.
hKLC4 T381I/+ worms have a severe motility defect. L4-stage worms swimming in buffer. Fiji wrMTrck plugin (Nussbaum-Krammer et al., 2015) was used to track each worm to measure the number of body bends per second (BBPS).
A humanized Caenorhabditis elegans model of hereditary spastic paraplegia-associated variants in KLC4
Disease Models and Mechanisms 2023. 16:None-None; doi: 10.1242/dmm.050076