Movie 1.
Super-resolution 3D structured illumination microscopy image showing the localization of â-DG in the perivascular space in the cortex of control mice. Immunostaining for β-DG (green) in combination with lectin (magenta) to visualize blood vessels and Hoechst (cyan) in the cortex of 2-month-old control mice. 3D reconstruction of a 40.96 × 40.96 × 3 μm z-stack. Note that there are no nuclei in the selected region in the control. This region of interest is also shown in Figure 5E.
The missense mutation C667F in murine β-dystroglycan causes embryonic lethality, myopathy and blood-brain barrier destabilization
Disease Models and Mechanisms 2024. 17:None-None; doi: 10.1242/dmm.050594