Movie 3.

A magnified view of 4T1 cells within a spheroid invading in 3D culture conditions. This video is a zoomed and cropped view of Movie 2 centered around the bottom edge of the spheroid. The play rate is 16 frames/sec (4,800 X real time). Arrows in the final frame indicate cells that correspond to the immunostained image in Fig. 7 of the manuscript.