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Movie 2.

Example of a C9-BAC mouse post-seizure displaying laboured breathing, reduced activity, orbital tightening, change in ear shape/position, piloerection. When picked up hindlimb clasping is evident.

A bacterial artificial chromosome mouse model of amyotrophic lateral sclerosis manifests ‘space cadet syndrome’ on two FVB backgrounds

Sophie E. Badger, Ian Coldicott, Ergita Kyrgiou-Balli, Adrian Higginbottom, Chloé Moutin, Kamallia Mohd Imran, John C. Day, Johnathan Cooper-Knock, Richard J. Mead, and James J. P. Alix

Disease Models and Mechanisms 2025. 18:None-None; doi: 10.1242/dmm.052221