To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Supplementary Movie 2 Local stimulation of wt GC with PBS. After vesicle photolysis and release of PBS, the GC continues the spontaneous navigation without significant changes in growth or direction. Characterization of prion protein function by focal neurite stimulation Ladan Amin, Xuan T. A. Nguyen, Irene Giulia Rolle, Elisa D'Este, Gabriele Giachin, Thanh Hoa Tran, Vladka Čurin Šerbec, Dan Cojoc, and Giuseppe Legname J Cell Sci 2016. 129:3878-3891; doi: 10.1242/jcs.183137 Download Original Video