Supplementary Movie 1
3D model of PIN arises from single cells. Movie was taken 2 hours after RWPE-1 cells were seeded on the Matrigel for 64 hrs. Notice that instead of moving into each other, single cells were dividing and rotating to form the structure.
A basal cell defect promotes budding of prostatic intraepithelial neoplasia
J Cell Sci 2017. 130:104-110; doi: 10.1242/jcs.188177