Supplemental Movie 4

Movie of Rab5-positive vesicles in vin-/- MEFs, and in vinFL-rescued cells
Images were acquired on a spinning-disk confocal microscope every second for 1 minute. Left cell is a vin-/- MEFs, right cell is a vin-/- MEF expressing GFP-vinFL (not shown), both are expressing RFP-Rab5. Note the faster movement of vesicles in the vin-/- MEF, compared to the cell rescued with vinFL. Scale bar indicates 10 μm.