Movie S2

Cells expressing BRCA1 form a mix of non-dividing and slow dividing cells. Cells were pre-stimulated with galactose for 4 hours, spread on a slide covered with an agarose pad containing galactose and immobilized with a coverslip. Vector cells were used as a control. Then, galactose (GAL) stimulation was monitored using transillumination videomicroscopy for 9 more hours. Movies were analyzed as in Movie S1.

Yeast cells reveal the misfolding and the cellular mislocalization of the human BRCA1 protein

Pierre Thouvenot, Lou Fourrière, Elodie Dardillac, Barbara Ben Yamin, Aurianne Lescure, Vincent Lejour, Xavier Heiligenstein, Jean-Baptiste Boulé, Maryse Romao, Graça Raposo-Benedetti, Bernard S. Lopez, Alain Nicolas, and Gaël A. Millot

J Cell Sci 2016. 129:4366-4378; doi: 10.1242/jcs.192880