Movie 2

Related to Figure 6. Time-lapse recordings of FX formation in NIH3T3 cells treated with DMSO, FAKi or FAKi + Srci.
The video shows NIH3T3 cells transfected with GFP-paxillin and treated with the indicated drugs. The below panel shows and the enlarged region indicated in the above panel (red boxes). Newly formed FXs at the cell periphery are indicated by the red arrows. Note the difference in FA formation in cells treated with DMSO compared to cells treated with FAKi + Srci. Images were taken every 2 minutes for 90 minutes. Images are played back at 5 frames/s. Both scale bars represent 10 μm.