Movie 1

Invadopodia formation in CTRL SUM159 cells in response to PDBu. SUM159 cells expressing a CTRL shRNA were infected with mCherry-cortactin adenovirus and plated on glass-bottom coverslips 24 h after infection. Cells were imaged at 37°C in a CO2 and humidity controlled environment. At indicated times cells were stimulated to form invadopodia with PDBu. Images were captured at 15 sec intervals for the duration of the movie.

A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells

Silvia M. Goicoechea, Ashtyn Zinn, Sahezeel S. Awadia, Kyle Snyder, and Rafael Garcia-Mata

J Cell Sci 2017. 130:1064-1077; doi: 10.1242/jcs.195552