Movie 3
Rac1 KO/rescue cells. Rac1 KO SUM159 cells were coinfected with adenovirus encoding mCherry-cortactin and mycRac1. At indicated times cells were stimulated to form invadopodia with PDBu. Images were captured at 15 sec intervals for the duration of the movie.
A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells
J Cell Sci 2017. 130:1064-1077; doi: 10.1242/jcs.195552