Movie 5

Invadopodia formation in SGEF KD cells. SUM159 cells stably expressing SGEF targeting shRNA were infected with mCherry-cortactin adenovirus as in Supp Movie 1. At indicated times cells were stimulated to form invadopodia with PDBu. Images were captured at 15 sec intervals for the duration of the movie.

A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells

Silvia M. Goicoechea, Ashtyn Zinn, Sahezeel S. Awadia, Kyle Snyder, and Rafael Garcia-Mata

J Cell Sci 2017. 130:1064-1077; doi: 10.1242/jcs.195552