Movie 6

Invadopodia formation in RhoG KD/rescue cells. RhoG KD SUM159 cells were co-infected with adenoviruses encoding mCherry-cortactin and shRNA resistant mycRhoG. At indicated times cells were stimulated to form invadopodia with PDBu. Images were captured at 15 sec intervals for the duration of the movie.

A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells

Silvia M. Goicoechea, Ashtyn Zinn, Sahezeel S. Awadia, Kyle Snyder, and Rafael Garcia-Mata

J Cell Sci 2017. 130:1064-1077; doi: 10.1242/jcs.195552