Time-lapse of transgenic oocytes microinjected mutant Ran (Tg-RanT24N) relative to Tg control, during meiosis-I for 14h. Time-lapse (15 minute intervals) movie of laser scanning confocal Z-stack reconstruction (every 5 μm) of Tg oocytes expressing H2B-RFP (red) and MAP-4- EGFP (green) that label chromosomes and spindle microtubules, respectively.