Movie 1
Wnt3a-treated cells show an increase in PTK7-positive vesicle number and motility
PTK7 expressing MCF7 cells were imaged before (left) and after (right) Wnt3a treatment using TIRF microscopy. Imaging was performed for 30 minutes. The movies show a representative 2 minute interval. Penetration depth: 150 nm.
PTK7 localization and protein stability is affected by canonical Wnt ligands
J Cell Sci 2017. 130:1890-1903; doi: 10.1242/jcs.198580