Movie 1

Myosin VI localizes to the periphery of gap junction plaques. NRK cells stably expressing Cx43-GFP (green) and HT-myosin VI were conjugated with the JF646-HaloTag ligand (red) before imaging using TIRF microscopy. Myosin VI is recruited to the periphery of Cx43 GJ plaques (see arrowheads, Figure 7D). Scale bar, 10 ┬Ám.

Myosin VI facilitates connexin 43 gap junction accretion

Bennett J. Waxse, Prabuddha Sengupta, Geoffrey G. Hesketh, Jennifer Lippincott-Schwartz, and Folma Buss

J Cell Sci 2017. 130:827-840; doi: 10.1242/jcs.199083