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Time-lapse imaging of a GFP-Sharpin overexpressing NCI-H460 cell. GFP fluorescence was bleached in part of the lamellipodium just before t = 0 sec.

The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex

Meraj H. Khan, Siiri I. Salomaa, Guillaume Jacquemet, Umar Butt, Mitro Miihkinen, Takahiro Deguchi, Elena Kremneva, Pekka Lappalainen, Martin J. Humphries, and Jeroen Pouwels

J Cell Sci 2017. 130:3094-3107; doi: 10.1242/jcs.200329

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