Loss of centrosome-spindle coupling induces centrosome mis-segregation.
Mitotic cell in wt tissue expressing Tub:GFP (green) and Spd-2:RFP (red). Laser assisted severing of the centrosome-spindle connection (red arrows) results in centrosome missegregation. Yellow arrows: centrosome attached to the spindle, white arrows: centrosome which mis-segregates.