Movie 7

A representative example of computer simulation is shown without KT sliding (associated with Figure 5B). Three-dimensional simulations are projected into X-Z and X-Y planes. KTs (dots) are colored as in Figure 5A. MT extension following KT-dependent rescue is shown in a dashed line (Gandhi et al., 2011). A gray line, which connects a KT (dot) to a MT extending from a spindle pole (black line), represents a KT-derived MT that facilitates KT loading onto a MT extending from a spindle pole (Kitamura et al., 2010).

Mechanisms mitigating problems associated with multiple kinetochores on one microtubule in early mitosis

Zuojun Yue, Shinya Komoto, Marek Gierlinski, Debora Pasquali, Etsushi Kitamura, and Tomoyuki U. Tanaka

J Cell Sci 2017. 130:2266-2276; doi: 10.1242/jcs.203000