Supplemental Movie 2

Mito-roGFP cells matched to those in Supplemental Movie 1 were pre-treated with nocodazole for 2 hrs prior to the addition of 10 mM MG132 and show no discernible retrograde trafficking and perinuclear accumulation of mitochondria due to depolymerization of microtubules.

A PGAM5–KEAP1–Nrf2 complex is required for stress-induced mitochondrial retrograde trafficking

Gary B. O'Mealey, Kendra S. Plafker, William L. Berry, Ralf Janknecht, Jefferson Y. Chan, and Scott M. Plafker

J Cell Sci 2017. 130:3467-3480; doi: 10.1242/jcs.203216