To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Supplemental Movie 6 Mito-roGFP cells transfected with Nrf2 siRNA and then treated with 10 mM MG132 show rapid fission and fusion, but attenuated mitochondrial retrograde trafficking and perinuclear clustering. A PGAM5–KEAP1–Nrf2 complex is required for stress-induced mitochondrial retrograde trafficking Gary B. O'Mealey, Kendra S. Plafker, William L. Berry, Ralf Janknecht, Jefferson Y. Chan, and Scott M. Plafker J Cell Sci 2017. 130:3467-3480; doi: 10.1242/jcs.203216 Download Original Video