Supplemental Movie 5

Representative movie of cells expressing Halo-iLID-Caax in combination with Tiam-Micro (red) and YPet-FN (green). Photoactivation occurs in the ROI highlighted with a white box. Cells are plated on fibronectin coated cover glass.

Cells lay their own tracks – optogenetic Cdc42 activation stimulates fibronectin deposition supporting directed migration

Seth P. Zimmerman, Sreeja B. Asokan, Brian Kuhlman, and James E. Bear

J Cell Sci 2017. 130:2971-2983; doi: 10.1242/jcs.205948