Video 7

Nocodazole effects on macrophages migrating to a wound. When migrating to a wound (in the presence of nocodazole) macrophages show rear detachment phenotype (see arrow). Front edge of the cell keeps migrating to the wound, while rear end stays attached. No neutrophils showed this phenotype. Upper panel: macrophage and neutrophils only, lower panel: macrophage, neutrophils and brighfield. Scale bar, 100μm

Live imaging reveals distinct modes of neutrophil and macrophage migration within interstitial tissues

Francisco Barros-Becker, Pui-Ying Lam, Robert Fisher, and Anna Huttenlocher

J Cell Sci 2017. 130:3801-3808; doi: 10.1242/jcs.206128